Table 3.
LD50 values of Alternaria mycotoxins currently available.
| Mycotoxin | Animal Species | Route of Exposure | LD50 (mg/kg b.w.) | Reference |
|---|---|---|---|---|
| AOH | Mouse (DBA/2) | intraperitoneal | >400 1 | [69] |
| AME | Mouse (DBA/2) | intraperitoneal | >400 1 | |
| TeA | Mouse | intravenous | 115 (female) | [70] |
| 162 (male) | ||||
| oral | 81 (female) | |||
| 186 (male) | ||||
| Mouse (ICR) | intravenous | 125 (male) | [71] | |
| intraperitoneal | 150 (male) | |||
| subcutaneous | 145 (male) | |||
| oral | 225 (male) | |||
| Rat | intravenous | 157 (female) | [70] | |
| 146 (male) | ||||
| oral | 168 (female) | |||
| 180 (male) | ||||
| Chicken embryo | injection | 548 2 | [72] | |
| White leghorn chicken | oral | 37.5 3 | [73] |
1 LD50 values of AOH and AME were not reached at the maximum dose tested, corresponding to 400 mg/kg, 2 Unit of measurement: µg/egg, 3 Information about sex not available.