Table 2.

Univariate analysis of clinical and biological parameters with Trimethylamine-N-oxide (TMAO) plasma concentrations (µmol/L).

Variable	rs	95% CI
Age, y	0.30	0.12 to 0.47	**
BMI, kg/m2	0.17	−0.02 to 0.35	ns
UA/C, mg/mmol	0.24	0.06 to 0.42	**
Uric Acid, µM	0.31	0.10 to 0.50	**
Bicarbonates, mM	−0.22	−0.43 to 0.01	*
Protein intake, g/kg/day	0.06	−0.21 to 0.31	ns
Triglycerides	0.17	−0.02 to 0.35	ns
HDL-cholesterol, mmol/L	−0.10	−0.28 to 0.09	ns
LDL-cholesterol, mmol/L	−0.16	−0.34 to 0.03	ns
TMA, µmol/L	−0.14	−0.32 to 0.06	ns
Choline, µmol/L	0.18	−0.01 to 0.36	ns
Betain, µmol/L	−0.05	−0.23 to 0.15	ns
Carnitine, µmol/L	0.20	0.01 to 0.38	*

Univariate correlations were performed using two-tailed Spearman’s test with 95% confidence interval for n = 61 to 113, according to the available data. * p < 0.05 ** p < 0.005. Abbreviations: A/CU: Urinary albumin/creatinine; BMI: body mass index; ns: non-significant; TMAO: trimethylamine-N-oxide.