Figure 7.

Molecular insight into the ID and fiber interaction. (A) Potential binding modes of arginine, classified as type I, II, or III. (B) Histogram showing the probability of forming a second arginine type III interaction as a function of sequential position when an existing type III interaction is made at position i. (C) Graphical representation of an ID binding to a fiber containing four repeat units of a self-assembled AcVES3 peptide. The right-most panel contains the entire sequence of AcVES3. The ID shown at top contains the minimal sequence necessary to make type III interactions with arginine located at positions i, and i + 6.