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. 2019 Dec 3;17:160. doi: 10.1186/s12964-019-0477-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — MORC2 can form a homodimer. a Schematic diagrams of the domain structure of human MORC2. CC, coiled-coil; CW-ZF, CW-type zinc finger. b-c HEK293T cells were transfected with Flag-MORC2, HA-MORC2 alone or in combination. After 48 h of transfection, total cellular lysates were subjected to IP analysis with an anti-Flag (b) or an anti-HA (c) antibody, followed by immunoblotting with the indicated antibodies. d HEK293T cells were transfected with HA-MORC2. After 48 h of transfection, total cellular lysates were subjected to cross-linking assay. e Purified MORC2 was visualized by coomasie brilliant blue staining. f Purified MORC2 was subjected to cross-linking assay and immunoblotting