Figure 2.

CD117 and tryptase expression in patients with hereditary alpha tryptasemia compared to irritable bowel syndrome. Panel A and B are representative CD117 and tryptase stains of duodenum of a patient with irritable bowel syndrome (IBS). Panel C and D are representative CD117 and tryptase from duodenum of a patient with hereditary alpha tryptasemia (HαT). In contrast with IBS, there are increased numbers of lamina propria mast cells in HαT as well as increased amount of tryptase release into the surrounding tissue. CD117 and tryptase are in brown. Slides are counterstained with hematoxylin. Bar length = 60 µm