Table 2.
Twenty‐one (18 female and 3 male) patients with HαT evaluated for the highest measured serum tryptase level, mast cell count in the gastrointestinal tract, existence of gastrointestinal dysmotility symptoms (Y = yes, N = no), existence of inflammation in the gut, and alpha and beta copy numbers of tryptase gene. Eleven patients from our cohort (n = 21) were randomly selected for isolating exosomes from the urine. Urinary exosomes were isolated from urine specimens collected between 9‐11 AM
| Sample | Max tryptase | Mast cells | GI dysmotility | Gut inflammation | Alpha copy number | Beta copy number |
|---|---|---|---|---|---|---|
| Female 1 | 9.2 | 47 | Y | Eosinophilic gastroenteritis | 3 | 2 |
| Female 2 | 12 | ND | Y | N | 2 | 3 |
| Female 3 | 12.8 | 28 | Y | N | 2 | 3 |
| Female 4 | 30 | 65 | Y | N | 2 | 3 |
| Female 5 | 13.4 | ND | N | Crohn's | 3 | 2 |
| Female 6 | 14.6 | 25 | N | Microscopic colitis | 2 | 3 |
| Female 7 | 13 | 54 | Y | N | 3 | 2 |
| Female 8 | 22 | 72 | Y | N | 2 | 3 |
| Male 1 | 11 | ND | ND | ND | 2 | 3 |
| Female 9 | 21 | 45 | Y | N | 2 | 3 |
| Female 10 | 13.4 | 35 | Y | N | 3 | 2 |
| Female 11 | 8.1 | 23 | Y | N | 3 | 2 |
| Female 12 | 9.9 | 42 | N | N | 3 | 2 |
| Female 13 | 13.1 | 59 | Y | Y | 2 | 3 |
| Female 14 | 13.1 | ND | Y | Autoimmune gastritis | 3 | 2 |
| Male 2 | 14.7 | ND | Y | N | 2 | 3 |
| Female 15 | 17.3 | ND | ND | ND | 4 | 2 |
| Female 16 | 15 | 52 | Y | N | 3 | 2 |
| Male 3 | 26.5 | NA | N | Crohn's | 2 | 3 |
| Female 17 | 10.5 | 60 | N | Crohn's | 3 | 2 |
| Female 18 | 23 | 102 | Y | Y | 2 | 3 |