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. Author manuscript; available in PMC: 2019 Dec 4.
Published in final edited form as: J Am Coll Cardiol. 2019 Jan 29;73(3):251–260. doi: 10.1016/j.jacc.2018.10.065

CENTRAL ILLUSTRATION. Previous Data Suggest Concentrations of hsTnI Predict Presence and Severity of Underlying Coronary Artery Disease.

CENTRAL ILLUSTRATION

In the present analysis, we found that high-sensitivity troponin I (hsTnI) concentrations predicted risk for incident death, myocardial infarction (MI), or hospitalization for unstable angina in a graded fashion. In adjusted analyses, high-sensitivity troponin I represented a strong independent predictor of these outcomes, and did so by predicting earlier rather than later events. These results suggest a possible role for measurement of troponin I using a very highly sensitive assay as a part of an overall strategy for evaluation of stable chest symptoms and possible coronary artery disease.