Table 2.

Univariate analysis for PFS

Variable	Univariable analysis
	HR	95% CI	p
Age
> 65 vs. < 65	1.161	0.512–2.638	0.720
Sex
Male vs. female	1.589	0.588–4.296	0.361
Smoking status
Smoker vs. never-smoker	0.970	0.410–2.293	0.945
Intracranial metastasis
Yes vs. no	1.398	0.469–4.173	0.548
Treatment
EP vs. EP + radiation	0.710	0.263–1.914	0.499
Lymphopenia
Yes vs. no	1.488	0.656–3.376	0.342
NLR
< 5.691 vs. > 5.691	0.406	0.149–1.107	0.078
PLR
< 186.26 vs. > 186.26	0.861	0.380–1.953	0.721
CD3+
< 38.90 vs. > 38.90	2.359	0.968–5.946	0.059
CD3+ CD4+
< 23.90 vs. > 23.90	0.935	0.409–2.137	0.874
CD3+ CD8+
< 32.00 vs. > 32.00	1.098	0.475–2.539	0.827
CD4+ CD25+Foxp3+
< 6.111 vs. > 6.111	1.431	0.625–3.274	0.396
CD4+ %divided
< 84.40 vs. > 84.40	2.306	0.962–5.527	0.061
CD8+ %divided
< 85.00 vs. > 85.00	5.252	1.724–16.000	0.004