Table 1.
Group of mice | a %CD4+ b | % CD8+ b |
---|---|---|
Control Ig | 23 ± 4.1 | 7.1 ± 2.2 |
Control C1 | 6.3 ± 1.5* | 2.5 ± 0.6* |
Control C2 | 26 ± 3.8 | 7.0 ± 2.5 |
Anti-CD4 treated | 6.0 ± 2.1* | 10 ± 2.9 |
Anti-CD8 treated | 27 ± 5.5 | 1.9 ± 0.5* |
Anti-CD4+ anti-CD8 treated | 6.7 ± 2.8* | 2.0 ± 1.2* |
aMice were immunized with OVA; received additional treatment with combined anti-idiotype and immune Ig; and also, anti-CD4 and/or anti-CD8 as indicated in Figs. 6 and 7
b% positive CD4+ and CD8+ cells in splenocytes of mice treated as in Fig. 6 and sacrificed 10 days after the last OVA immunization. Data show means (± SD) for groups of 7 mice
* p < 0.05 compared with first row, control Ig group (no anti-idiotype Ig/Immune Ig and no anti-CD4/-CD8)