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. 2019 Dec 4;20:926. doi: 10.1186/s12864-019-6231-y

Table 3.

Summary of QTL detected by GEMMA for WW in U.S. Gelbvieh beef cattle

Chr_Mb MAF -log10 P-value Supporting SNPs Positional Candidate Genes Lead SNP Location Scientific Precedence [reference]; organism; trait
6_39a 0.289 18.32 107 NCAPG Exonb [18, 21, 30, 3539]; Cattle, chicken; stature, calving ease and growth traits association, SimAngus mid-test metabolic weight association, fetal growth, carcass trait association, average daily gain and daily feed intake, muscle mass
14_25a 0.398 10.69 2 PLAG1 3’UTR [2, 14, 18, 21, 30, 3234]; Cattle; SimAngus mid-test metabolic weight association, carcass weight, stature, body weight and milk
5_60a 0.046 8.83 2 LOC527216, LOC788998 Intergenic NA
6_36a 0.214 7.95 29 CCSER1 Intron [14, 60]; Cattle, human; body and carcass weight association, regulator of mitosis
14_26a 0.415 7.90 11 IMPAD1, FAM110B Intergenic [30, 32, 34, 40]; Cattle; SimAngus mid-test metabolic weight association, carcass weight association, stature and body weight association, bone and cartilage system
6_42a 0.340 7.77 3 KCNIP4 Intron [39, 41, 42]; Chicken, cattle, human; growth and muscle mass trait association, potassium channel activity
6_38a 0.220 7.70 9 HERC6, PPM1K Intergenic [49, 58, 59]; Cattle; milk, fat, and protein yield, metabolic processes, feed efficiency association
6_41a 0.238 6.46 4 LOC782905, SLIT2 Intergenic [39, 4953]; Cattle, chicken, human; milk fat and protein association, organ and muscle weight, development of central nervous system, tumor suppressor activity
6_37a 0.325 5.97 5 SNCA, GPRIN3 Intergenic [6164]; Human, goat, equine; neurological regulation, milk and meat associations, tendon tissue association
6_34a 0.295 5.36 4 LOC100336621, LOC104972717 Intergenic NA

a Indicates QTL was detected in EMMAX analysis

b Indicates a predicted nonsynonymous mutation Ile➔Met, exon 9