Table 6.
Summary of GxE QTL detected by GEMMA for WW in U.S. Gelbvieh beef cattle
| Chr_Mb | MAF | -log10 P-value | Supporting SNPs | Positional Candidate Genes | Lead SNP Location | Scientific Precedence [reference]; organism; trait |
|---|---|---|---|---|---|---|
| 2_18 | 0.012 | 5.22 | 2 | TTN | Exona | [77–79]; Rabbit, rat, human; aids in myofibrillar assembly, positioning of myosin filaments in muscle, coordinates multiple signaling pathways for gene activation, protein folding, quality control and degradation, heart disease relation |
a Indicates a predicted nonsynonymous mutation Arg➔Gln, exon 304