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. 2019 Oct;189(10):1986–2001. doi: 10.1016/j.ajpath.2019.07.003

Figure 6.

Figure 6

Mice were treated with 300 mg/kg acetaminophen (APAP), followed by treatment with tranexamic acid for 48 hours, as detailed in Materials and Methods. A and B: Proliferating cell nuclear antigen (PCNA) was detected in liver sections from mice treated with either APAP and water (A) or APAP and tranexamic acid (B). Positive staining appears brown in the photomicrographs. C: The number of PCNA-positive hepatocytes was quantified. Data are expressed as means ± SEM (C). n = 5 mice per group (C). Original magnification, ×200 (A and B).