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Transmission electron microscopy of the corneal primary stroma at E6. Orthogonality between adjacent micro-lamellae is evident in the immediate sub-epithelial stroma (A), with fibrils appearing as dark circles running perpendicular to the image plane and as long thin structures running within the image plane. Epithelial basal lamina is indicated by white arrow. Cells and cell processes within the primary stroma are closely apposed to collagen fibrils (B–D).
