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The perfusion signal in a single slice of the brain of a healthy volunteer following PCASL with a: no offsets in the labelling plane, b: offsets, uncorrected in the encoding and c: an offset corrected encoding. d: Field map of the labelling plane after shim adjustments to generate phase offsets. e: Mean SNR ±standard deviation of the perfusion signal across all subjects. *P < 0.05.
