Fig. 3.

Effect of TCE and TaClo on wild type and A30P α-synuclein overexpressing C57BL/6 Mouse Spatial Learning Assessed by the Barnes Maze.

Average (A) primary latency, (B) total latency (both sec), (C) primary errors and (D) total errors to find target of vehicle (10 ml/kg olive oil), TCE (100 mg/kg) or TaClo (2 mg/kg), treated wild type or A30P α-synuclein overexpressing C57BL/6 mice over time, quadruplicate trials. Data presented as mean ± SEM (n = 8–10). (A and B) Significant difference over time (p < 0.001), No significant difference between treatment groups or of treatment over time, Two-Way Repeated Measures ANOVA.