Table 2. Clinical characteristics of patients with intermediate-high risk PE ( n = 97) who did or did not receive thrombolysis .
| Received thrombolysis N = 17 |
Did not receive thrombolysis N = 80 |
p -Value | |
|---|---|---|---|
| Clinical characteristics, | |||
| Age, y (mean ± SD) | 56.6 ± 20.3 | 73.3 ± 13.7 | < 0.001 |
| Age > 80 y | 0 (0) | 28 (35) | < 0.01 |
| Male gender | 8 (47) | 35 (44) | 1.00 |
| Risk factors for VTE, | |||
| Cancer a | 1 (5.9) | 6 (7.5) | 1.00 |
| Recent surgery b | 1 (5.9) | 6 (7.5) | 1.00 |
| History of VTE | 2 (12) | 6 (7.5) | 0.63 |
| Immobilization c | 3 (18) | 19 (24) | 0.75 |
| Comorbid diseases | |||
| Chronic lung disease | 0 (0) | 10 (13) | 0.20 |
| Chronic heart disease | 0 (0) | 5 (6.3) | 0.58 |
| Clinical symptoms and signs at presentation | |||
| Syncope | 4 (24) | 25 (31) | 0.77 |
| Chest pain | 12 (71) | 31 (39) | 0.03 |
| Dyspnea | 13 (76) | 63 (79) | 1.00 |
| Heart rate ≥ 110/min | 13 (76) | 29 (36) | 0.02 |
| Arterial oxyhemoglobin saturation (SaO 2 ) < 90% | 7 (41) | 50 (63) | 0.17 |
| SBP < 100 mm Hg | 5 (29) | 3 (3.8) | < 0.01 |
Abbreviations: PE, pulmonary embolism; SBP, systolic blood pressure; SD, standard deviation; VTE, venous thromboembolism.
a
Active or under treatment in the last year.
b
In the previous month.
c
Immobilized patients defined as nonsurgical patients with limited mobility (i.e., total bed rest with bathroom privileges) for ≥ 4 days in the month prior to PE diagnosis.