Table 3. Characteristics of tests performed 48 hours after PE diagnosis for predicting 30-day adverse events.

		Systolic blood pressure normalization	Heart rate normalization	Cardiac troponin I normalization	Brain natriuretic peptide normalization	Echocardiography normalization
Measurement normalization, % (95% CI)		82 (73–90)	86 (77–92)	78 (67–86)	72 (61–81)	33 (23–44)
Sensitivity, % (95% CI)	Complicated course	82 (48–97)	91 (57–100)	73 (39–93)	82 (48–97)	64 (32–88)
	All-cause mortality	75 (36–96)	100	63 (26–90)	75 (36–96)	75 (36–96)
	PE-related mortality	60 (17–93)	100	80 (30–99)	80 (30–99)	100
Specificity, % (95% CI)	Complicated course	92 (83–97)	97 (90–100)	85 (75–92)	80 (68–88)	32 (22–44)
	All-cause mortality	88 (78–94)	95 (87–98)	82 (71–89)	77 (65–85)	34 (24–46)
	PE-related mortality	85 (75–92)	91 (82–96)	81 (71–89)	75 (64–84)	35 (25–47)
Positive predictive value, % (95% CI)	Complicated course	60 (33–83)	83 (51–97)	42 (21–66)	38 (20–59)	12 85.5–24)
	All-cause mortality	40 (17–67)	67 (35–89)	26 (10–51)	25 (11–47)	11 (4.4–22)
	PE-related mortality	20 (5.3–49)	42 (17–71)	21 (7.0–46)	17 (5.5–38)	8.8 (3.3–20)
Negative predictive value, % (95% CI)	Complicated course	97 (89–100)	99 (92–100)	95 (86–99)	97 (88–99)	86 (66–95)
	All-cause mortality	97 (89–100)	100	95 (86–99)	97 (88–99)	93 (75–99)
	PE-related mortality	97 (89–100)	100	98 (91–100)	98 (90–100)	100
Positive likelihood ratio (95% CI)	Complicated course	10 (4.5–23)	34 (8.5–134)	4.9 (2.5–9.4)	4.0 (2.4–6.9)	0.9 (0.6–1.5)
	All-cause mortality	6.4 (3.1–13)	19 (7.4–50)	3.4 (1.7–7.0)	3.2 (1.8–5.7)	1.1 (0.7–1.7)
	PE-related mortality	4.0 (1.7–9.7)	11 (5.6–23)	4.3 (2.3–8.0)	3.2 (1.8–5.7)	1.5 (1.3–1.8)
Negative likelihood ratio (95% CI)	Complicated course	0.2 (0.1–0.7)	0.1 (0.0–0.6)	0.3 (0.1–0.8)	0.2 (0.1–0.8)	1.1 (0.5–2.6)
	All-cause mortality	0.3 (0.1–0.9)	0	0.5 (0.2–1.1)	0.3 (0.1–1.1)	0.7 (0.2–2.6)
	PE-related mortality	0.5 (0.2–1.4)	0	0.3 (0.0–1.4)	0.3 (0.1–1.6)	0

Abbreviations: CI, confidence interval; PE, pulmonary embolism.