Table 1. Baseline demographics.
Characteristic | Tricuspid valvectomy (n=106) | Tricuspid valve replacement (n=646) | Overall (n=752) | P value |
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Pooled value [95% CI] |
No. of studies | No. of patients | I2 (%) | Pooled value [95% CI] |
No. of studies | No. of patients | I2 (%) | Pooled value [95% CI] |
No. of studies | No. of patients | I2 (%) | |||||
Baseline demographics | ||||||||||||||||
Age (years) | 29 [12–46]† | 1 | 7 | NA | 37 [26–47] | 8 | 73 | 87* | 36 [26–45] | 9 | 80 | 85 | 0.44 | |||
Male (%) | 48 [38–58] | 3 | 47/98 | 0 | 62 [50–74] | 10 | 308/589 | 45 | 55 [47–62] | 11 | 355/687 | 29 | 0.07 | |||
Systemic hypertension (%) | 20 [11–32] | 2 | 18/91 | 21 | 35 [31–39] | 2 | 179/516 | 0 | 26 [17–37] | 2 | 197/607 | 66* | 0.02 | |||
Indications for surgery | ||||||||||||||||
Persistent sepsis (%) | 47 [24–71] | 2 | 7/15 | 0 | 62 [31–86] | 7 | 25/51 | 61* | 54 [33–74] | 8 | 32/66 | 49 | 0.45 | |||
Septic pulmonary embolism (%) | 74 [28–95] | 2 | 26/33 | 78* | 38 [16–66] | 7 | 25/72 | 64* | 48 [25–72] | 7 | 51/105 | 72* | 0.18 | |||
Microorganisms | ||||||||||||||||
Staphylococcus Aureus (%) | 93 [74–98] | 2 | 30/32 | 0 | 49 [38–61] | 8 | 37/73 | 0 | 66 [48–80] | 9 | 67/105 | 48 | <0.01 | |||
Streptococcus (%) | 3 [0–21] | 2 | 0/32 | 0 | 33 [20–50] | 3 | 12/36 | 0 | 23 [10–46] | 5 | 12/68 | 40 | 0.01 | |||
Enterococcus (%) | 3 [0–21] | 2 | 0/32 | 0 | 25 [12–45] | 2 | 7/28 | 0 | 15 [4–42] | 4 | 7/60 | 41 | 0.04 | |||
Fungal (%) | 7 [1–35] | 2 | 1/32 | 30 | 60 [19–90] | 2 | 3/5 | 0 | 23 [4–67] | 4 | 4/37 | 58* | 0.03 |
†, median 29 years, range, 20–46 years; *, heterogeneity P<0.05 (significant data heterogeneity present). NA, not applicable.