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Impairment of mitophagy compromises the extended CLS of methionine-restricted yeast. (A) The mitophagy-related factors Atg32, Uth1, and Dnm1 are all required for the maximal extension of CLS by G-MR. (B) In contrast, deletion of these factors from otherwise wild-type cells does not negatively impact CLS. For both panels, Control denotes the CLS of wild-type cells and bars denote SEM.
