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. 2019 Dec 4;187(1):13. doi: 10.1007/s00604-019-3975-7

Graphical abstract.

Graphical abstract

Schematic representation of the aggregation of aptamer-functionalised nanoparticles in the presence of interleukin-6 (IL-6). The presence of mouse IL-6 in a mixed protein solution leads to a visible colour change, and a change in the absorption spectrum of the nanoparticles.