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. 2019 Dec 4;9:18334. doi: 10.1038/s41598-019-54677-y

Table 3.

Stratified analysis for all-cause mortality in 5 year cancer survivors with pre-existing depression as compared to those without pre-existing depression.

No Pre-existing Depression Pre-existing Depression
Age (ref)
  <60 years 1 1.31 (0.64–2.66)
  ≥60 years 1 1.61 (1.16–2.23)**
Sex (ref)
  Men 1 1.78 (1.25–2.55)**
  Women 1 1.11 (0.94–1.31)
Insurance Typea (ref)
  Employee Insured 1 1.62 (1.12–2.33)*
  Self-employed 1 1.51 (0.95–2.41)
Insurance Premium (Quartile) (ref)
  1st/2nd 1 1.41 (0.84–2.38)
  3rd/4th 1 1.61 (1.12–2.31)**
Body Mass Index (kg/m2 (ref)
  <25 1 0.94 (0.44–2.00)
  ≥25 1 1.73 (1.26–2.40)***
Fasting Serum Glucose (mg/dL) (ref)
  <126 1 1.12 (0.40–3.11)
  ≥126 1 1.62 (1.19–2.21)**
Cholesterol level (mg/dL) (ref)
  <240 1 0.38 (0.05–2.84)
  ≥240 1 1.66 (1.23–2.24)***
Alcohol Consumption (times/week) (ref)
  1–2 1 1.43 (1.04–1.99)*
  ≥3 1 2.15 (1.10–4.24)*
Physical Activity (times/week) (ref)
  1–2 1 1.44 (1.02–2.02)*
  ≥3 1 2.01 (1.09–3.72)*
Smoking status (ref)
  Non-smoker 1 1.64 (1.19–2.29)**
  Past-smoker 1 1.67 (0.58–4.79)
  Current smoker 1 1.11 (0.46–2.71)
Charlson Comorbidity Index (ref)
  <2 1 1.27 (0.77–2.08)
  ≥2 1 1.86 (1.29–2.70)**

Data above are presented as HR (95%) adjusted for age, sex, place of residence, insurance type, insurance premium, and presence of disability, BMI, fasting serum glucose, total cholesterol, cigarette smoking, alcohol consumption, physical activity, and CCI (except for the variable belonging to the stratified category).

aMedical aid category is omitted from the subgroup analysis due to a significantly low number of subjects.

NOTE: Statistical significance is noted as *P < 0.05, **P < 0.01, ***P < 0.001.