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. 2019 Dec 4;10:5522. doi: 10.1038/s41467-019-13381-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Hydrodynamic size of products produced from RCA on SiNP-primer-template (SiNP-P-T) particles in the presence or absence of T4 DNA ligase. All data are represented by mean ± S.D. of triplicate samples. b Trajectory maps and c MSD values of tracer particles in S100 after 0 and 48 h of RCA. The yellow curves in c represent the average MSD. d, e Representative HAADF-STEM imaging (first column), EDS elemental mapping (second to sixth column) and f relative atomic ratios of N and P to Si of S100 after 0 and 48 h of RCA. Data represent mean ± S.D. of the EDS measurements determined from 50 particles in four random areas.