Table 1.

Linear regression analysis of association of clinical factors and DNA methylation adjusted for age and sex.

Clinical factors	m6A DNA			5mC DNA
	β	95% CI	P	β	95% CI	P
Plaque size (mm3)	−0.289	−0.825 to −0.068	<0.001	−0.076	−0.347 to 0.127	0.337
CIMT (mm)	−0.443	−1.124 to −0.103	<0.001	−0.065	−0.170 to 0.115	0.396
Hcy (µmol/L)	−0.162	−0.423 to −0.024	0.023	−0.115	−0.521 to −0.025	0.031
VB12 (pg/ml)	0.171	0.012 to 0.424	0.017	−0.025	−0.103 to 0.087	0.730
Folic acid (ng/ml)	0.082	−0.143 to 0.247	0.259	0.031	−0.129 to 0.294	0.662
Albumin (g/L)	0.257	0.019 to 0.532	<0.001	−0.008	−0.303 to 0.387	0.911
LDL (mmol/L)	−0.175	−0.494 to −0.089	0.023	0.020	−0.126 to 0.272	0.776
TG (mmol/L)	0.057	−0.197 to 0.202	0.426	−0.089	−0.301 to 0.251	0.208
HDL (mmol/L)	0.084	−0.102 to 0.347	0.235	−0.026	−0.378 to 0.324	0.706
ALT (U/L)	−0.077	−0.236 to 0.173	0.282	0.044	−0.208 to 0.325	0.530
AST (U/L)	−0.062	−0.279 to 0.368	0.383	0.019	−0.107 to 0.305	0.788
ALP (U/L)	−0.035	−0.207 to 0.159	0.616	0.040	−0.246 to 0.301	0.561
Urea (mmol/L)	−0.057	−0.349 to 0.267	0.420	−0.061	−0.142 to 0.108	0.378
UA (µmol/L	0.115	−0.134 to 0.360	0.103	0.107	−0.214 to 0.480	0.125
Apo A (g/L)	0.075	−0.141 to 0.342	0.328	−0.040	−0.237 to 0.253	0.592
Apo B (g/L)	−0.072	−0.416 to 0.504	0.332	0.035	−0.241 to 0.358	0.635
TC (mmol/L)	0.051	−0.312 to 0.465	0.487	−0.042	−0.475 to 0.349	0.557

CIMT carotid intima-media thickness, Hcy homocysteine, VB12 vitamin B12, LDL low-density lipoprotein, TG triglycerides, HDL high-density lipoprotein, ALT alanine aminotransferase, AST aminotransferase, ALP alkaline phosphatase, Apo A apolipoprotein A, Apo B apolipoprotein B, TC total cholesterol

The bold, significant difference