Table 1.

Summary of trio WGS and identification of DNMs.

Monkey ID	Relationship	Treatment group	Depth	On-target ratio	Candidate DNMs	Final SNVs	Final INDELs
rmFwt	Father	Wildtype	45.81	–		–	–
rmM1wt	Mother-1	Wildtype	46.23	–		–	–
rmM2wt	Mother-2	Wildtype	45.23	–		–	–
rmO1ko	Offspring-1	Cas9-treat	48.39	0.435	1324	34	5
rmO2-Bko	Offspring-2-brain	Cas9-treat	45.98	0.953	1169	29	3
rmO2-Mko	Offspring-2-muscle	Cas9-treat	44.85	0.938	1188	30	3
rmO2-Lko	Offspring-2-liver	Cas9-treat	45.35	0.952	1,230	29	2
rmO3ko	Offspring-3	Cas9-treat	46.84	0.122	1267	38	1
rmO4ko*	Offspring-4	Cas9-treat	45.92	0	1531	30	1
rmO5ko	Offspring-5	Cas9-treat	47.60	0.321	1847	37	1
cmFwt	Father	Wildtype	64.08	–		–	–
cmMwt	Mother	Wildtype	76.11	–		–	–
cmOki	Offspring	Cas9-treat	68.42	–	6060	32	3