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. 2019 Dec 4;10(12):917. doi: 10.1038/s41419-019-2156-2

Fig. 5. BH3-mimetics displace proapoptotic BCL-2 proteins from antiapoptotic targets.

Fig. 5

a MOLM-13 cells were treated with 1 μM ABT-199 for 8 h. b MOLM-13 or MONO-MAC-6 cells were treated with 1 µM S63845 for 4 or 2 h, respectively. a, b MCL-1, BCL-xL and BCL-2 were immunoprecipitated followed by analysis of proapoptotic binding partners by Western blotting with GAPDH serving as loading control. The input is shown for basal protein expression levels. * indicates IgG band.