Table 3.

Li-influenced changes in RNA levels of genes implicated in AD.

Gene	Product	Change	Ontologies	AD assoc	Co-exp.	PPI
BMP4	bone morphogenetic protein 4	+51%	Regulation Cell comp.org Cell Proc Developmental Metabolic Processes	83–85,109	absent	present
PTMA	prothymosin α	+48%		110	present	present
SOX5	SRY box 5	−45%	Regulation Developmental Metabolic Processes	111	absent	present
RAB3A	ras-related protein 3A	−44%		112,113	present	present
NRXN3	neurexin-3 α	−43%		88–90	present	absent
GLIS3	GLIS family zinc finger 3	−42%	Developmental Multicellular Processes	114,115	present	present
HS6ST2	heparan sulfate 6-O-sulfotransferase 2	+41%		116	present	absent
NMB	neuromedin B	+41%		117–120	present	absent
HGF	hepatocyte growth factor	+38%		121–124	absent	present
GPRC5B	G-protein coupled receptor family C group 5 member B	−34%	Regulation Cell comp.org Immune Metabolic Proc Multicellular Processes Response to Stimulus	125	present	present
YAP1	yes-associated protein 1	−32%	Regulation Metabolic Processes	126	present	present
SMAD6	SMAD family member 6	−29%	Regulation Metabolic Processes Response to Stimulus Signaling	127	absent	present
GREM2	gremlin 2	−28%		128	present	absent
IRS1	insulin receptor substrate 1	−28%	Regulation	129	present	present
IGFBP2	insulin-like growth factor binding protein 2	+28%		130–133	absent	present
CUX2	cut-like homeobox 2	−27%	Regulation Localization Metabolic Processes	134	absent	present
ZWINT	ZW10 interacting kinetochore protein	+27%		135	present	present
PPARG	peroxisome proliferator-activated receptor γ	−26%	Regulation Developmental Localization Metabolic Processes Response to Stimulus	86,87	present	present