Table 1.

DEG per time point after Caco-2 cells exposure to TiO₂ NPs.

	FC ≥ 1.2			FC ≥ 1.5			FC ≥ 1.8
	2 h	4 h	24 h	2 h	4 h	24 h	2 h	4 h	24 h
|FC|	3827	5220	3916	806	797	623	253	155	248
Upregulated	2004	2051	1978	595	503	234	214	63	169
Downregulated	1823	3169	1938	211	294	389	39	92	79
p.val < 0.05	532	1991	470	532	470	1991	532	1991	470
adj.p.val < 0.05	0	3	0	0	0	3	0	3	0
|FC| and p.val	434	1532	432	234	242	281	121	88	129
|FC| and adj.p.val	0	3	0	0	0	1	0	1	0

A LIMMA test was used in R with a fold change (FC) of > = 1.2, 1.5 or 1.8 and a p-value < 0.05. DEG used for the analysis are shown in bold. |FC| = Fold Change, p.val = p-value, adj.p.val = adjusted p-value.