Figure 5.
Multivariate statistical analysis distinguished the phenolic compounds on the antibacterial activity against Staphylococcus aureus. (A) OPLS-DA and (B) PLS-DA analysis during the rainfall and drought periods. (C) VIP analysis (Variable Importance in Projection) extracted from the PLS-DA plot identified principal phenolic compounds (guttiferones) and classes of flavonoids (flavanones) responsible by anti-staphylococcal activity during the seasonal study. The OPLS-DA model was validated by CV-ANOVA, p = 0.000004 (p < 0.05), F = 12.47. The PLS-DA model was validated by CV-ANOVA, p = 0.000003 (p < 0.05), F = 12.90.