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Mechanisms of assisting thrombolysis using ultrasound. A) Ultrasound forces cause ELIP to deliver a payload of PA near a thrombus. B) Sonic forces cause acoustic streaming that induces flow and improves transport of PA to a thrombus. C) Sonic forces cause cavitation, which imparts mechanical energy into the thrombus and initiates degradation even in the absence of PA. D) Microbubbles increase the frequency of cavitation and accelerate lysis. See Table 1 for details and references.
