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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Oct 28;205:107696. doi: 10.1016/j.drugalcdep.2019.107696

Table 3.

Intraclass correlations and latent class heritability for monozygotic and dizygotic twins.

Class Twin 2
Alcohol Co-Use Sim. Alcohol Use Sim. Tobacco Use Sim. ATD Use
Class Twin 1 Monozygotic Female Twins (208 pairs)
1 0.54 0.33 −0.39 −0.20
2 0.21 0.23 −0.14 −0.17
3 −0.26 −0.21 0.32 0.01
4 −0.26 −0.17 0.09 0.26
Dizygotic Female Twins (148 pairs)
1 0.20 0.09 −0.09 −0.12
2 0.21 0.21 −0.18 −0.10
3 −0.06 −0.08 0.12 −0.02
4 −0.26 −0.15 0.11 0.21
Monozygotic Male Twins (98 pairs)
1 0.42 0.06 0.00 −0.09
2 0.09 0.26 −0.06 −0.28
3 −0.05 −0.27 0.22 0.13
4 −0.07 −0.05 −0.13 0.21
Dizygotic Male Twins (75 pairs)
1 0.09 0.08 −0.04 −0.05
2 0.03 0.15 −0.10 −0.08
3 −0.05 −0.13 0.15 0.03
4 −0.01 −0.08 0.01 0.08
Dizygotic Opposite Sex Twins (130 pairs)
Class Female Twin Class Male Twin
1 0.04 0.19 −0.08 −0.15
2 0.02 0.08 −0.02 −0.07
3 −0.02 −0.06 0.01 0.06
4 −0.01 −0.15 0.06 0.10
Estimated Heritability of Latent Class Membership
Alcohol Co-Use Sim. Alcohol Use Sim. Tobacco Use Sim. ATD Use
Females 68% 4% 40% 10%
Males 66% 22% 14% 26%
Full Sample 58% 12% 30% 14%