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. 2019 Dec 4;39(12):BSR20192779. doi: 10.1042/BSR20192779

Figure 1. Up-regulated circZFR in bladder cancer and its association with poor prognosis of bladder cancer patients.

Figure 1

(A) The high expression levels of circZFR in 104 paired bladder cancer tissues compared with adjacent normal tissues by qRT-PCR (**P < 0.01). (B) The expression of circZFR in bladder cancer cell lines and human normal bladder epithelial cell (CCC-HB-2), **P < 0.01 compared with CCC-HB-2. (C–F) The expression levels of circZFR in bladder cancer patients with lymph node status, grades, pathological T stages, recurrence status. (G and H) Kaplan–Meier analysis and log rank test showed that patients with high circZFR expression had short progression-free survival (PFS) and overall survival (OS). (I) The receiver operating characteristic (ROC) curve showed the diagnostic value by using circZFR expression.