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. 2019 Oct 24;9(12):4007–4017. doi: 10.1534/g3.119.400635

Table 1. Trafficking genes affecting Rh1, Crb, and Eys distribution in PRCs.

Cargo Gene CG # RNAi line tested Phenotype
Rh1 Bet3 CG3911 BDSC: 38302, VDRC: 21738 Cytoplasmic Rh1
CdGAPr CG10538 BDSC: 6437, 38279 Cytopslamic Rh1
twf CG3172 BDSC: 35365, 57375, VDRC: 25817 Cytoplasmic Rh1
Crb & Eys sqh CG3595 BDSC: 33892 & 32439 Larger IRS, longer Crb stained membrane, rectangular rhabdomeres for some ommatidia
Rph CG11556 BDSC: 25950, VDRC: 52438 Larger IRS, longer Crb stained membrane, rectangular rhabdomeres
Eys & Rh1 Dhc64c CG7507 BDSC: 36698, 28749, 36583 Increase in cytoplasmic Rh1, cytoplasmic Eys and decrease in IRS size
Khc CG7765 BDSC: 25898, 35409 Cytoplasmic Rh1 and Eys
Rab2 CG3269 BDSC: 28701, 34922, VDRC: 34767 Missing/smaller rhabdomeres and reduced IRS size
ExocystExo70 Exo84 Sec10 Sec15 Sec5 Sec6 CG7127 CG6095 CG6159 CG7034 CG8843 CG5341 BDSC: 55234 BDSC: 28712 BDSC: 27483 BDSC: 27499 BDSC: 27526 VDRC:105836, 22079 Increase in cytoplasmic Rh1, cytoplasmic Eys and decrease in IRS size
Eys & Rh1 & Crb Chc CG9012 BDSC: 27530, VDRC: 23666 Reduced Crb, cytoplasmic Eys and Rh1
aux CG1107 BDSC: 35310, 39017 Reduced Crb, cytoplasmic Eys and Rh1
shi CG18102 BDSC: 36921, 28513 Cytoplasmic Eys, Crb, and Rh1 and retinal degeneration
TSG101 CG9712 BDSC: 35710, VDRC: 23944 Cytoplasmic Rh1, smaller/missing rhabdomeres, smaller IRS and less Crb
Slh CG3539 BDSC: 34335, 50940 Reduction of Rh1, Eys and Crb
Shrb CG8055 BDSC: 38305, VDRC: 106823 Cytoplasmic Eys, Crb, and Rh1 and retinal degeneration
V-ATPase Vha26 Vha100-1 CG1088 CG1709 BDSC: 38996 BDSC: 26290 Cytoplasmic accumulation of Rh1, Crb and Eys
Klc CG5433 BDSC: 36795, 33934, 42597 Cytoplasmic Rh1 and Eys and reduction in Crb levels
Rab1 CG3320 BDSC: 27299, VDRC: 330620 Reduction in Crb, Eys and Rh1
Rab5 CG3664 BDSC: 30518, 34832 Many ommatidia disintegrated; less affected ommatidia had larger IRS, longer Crb stained stalks and degenerated rhabdomeres; reduced Rh1 at the rhabdomeres
MyosinV CG2146 VDRC: 16902 BDSC: 55740 Ectopic rhabdomeres at the basolateral membrane. Basolateral Eys and Crb. Cytoplasmic Rh1 and Eys.
Avl/Syx7 CG5081 BDSC: 29546, VDRC:107264 Larger IRS, basolateral Rh1, longer Crb stained stalks
Sec71 CG7578 BDSC: 32366, VDRC:100300 Significant reduction in Crb, Eys and Rh1, rhabdomeres absent