Figure 2.

Apoptosis levels vary across genetic background in p53 and rpr models of apoptosis-induced degeneration. Apoptosis induced by overexpression of p53 (A) or rpr (B), as measured by adult eye size, varies across different genetic backgrounds. DGRP strains are arranged along the X-axis from smallest to largest. Each point represents the median eye size of an individual DGRP strain, while the error bars represent the standard deviation of eye size for that strain. Representative images of GMR > p53 eyes (C) or GMR-rpr eyes (D) in different DGRP backgrounds demonstrate the phenotypic variation quantified in panels A and B.