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. 2019 Dec 11;9(12):4019–4027. doi: 10.1534/g3.119.400752

Figure 1.

Figure 1

Diploid and Tetraploid C.albicans are sensitive to antifungals. A) Diploid colony forming units (CFUs) following 24-hr exposure to 1μg/mL or 10μg/mL fluconazole (‘FLU’, light and dark purple bars) and 0.25μg/mL or 2.5μg/mL caspofungin (‘CAS’, light and dark green bars) treatments. Bars represent the mean of 3 independent experiments (black symbols), and the error bars indicate +/− SEM. The dashed line and shaded box represent the mean and +/− SEM of the no-drug treatment. Asterisks indicate drug treatments that differ significantly from the no-drug treatment (* P < 0.05; ** P < 0.01; unpaired Mann-Whitney U-test). B) Tetraploid colony forming units. Data are displayed and analyzed the same as (A). C) The relative reduction of tetraploid CFUs compared to diploid CFUs. Data are displayed and analyzed similarly to (A).