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. 2019 Nov 22;2019:3518378. doi: 10.1155/2019/3518378

Figure 7.

Figure 7

Expression and prognostic value of TOP2A in HCC. (a–e) The expression data collected from 4 datasets from ONCOMINE indicated that TOP2A expression was upregulated in HCC tissues compared with the normal controls (all P < 0.05). (f) Expression of TOP2A was increased in HCC cells based on the data from CCLE. (g) The Kaplan-Meier survival curves revealed that the high TOP2A expression predicted worse overall survival compared with the low TOP2A expression in HCC patients (log-rank P = 0.00012). (h) No significantly different survival times were found between patients with high TOP2A and patients with low TOP2A at tumor stage 1 (log-rank P = 0.1). (i) High TOP2A expression predicted worse overall survival compared with the low TOP2A expression in HCC patients at tumor stage 2 (log-rank P = 0.0073). (j) High TOP2A expression predicted worse overall survival compared with the low TOP2A expression in patients with HCC at tumor stage 3 (log-rank P = 0.00066).