Table 2.
Functional and pathway enrichment analyses of DEGs in HCC.
| Term | Description | P value | Count | Gene name |
|---|---|---|---|---|
| GO:0045926 | Negative regulation of growth | 9.99E-07 | 7 | MT1M, GPC3, MT1E, MT1H, MT1X, MT1G, MT1F |
| GO:0051301 | Cell division | 1.30E-05 | 15 | CDC6, CDK1, NUF2, TPX2, CENPF, NDC80, CDC20, UBE2C, CCNB1, CCNB2, MAD2L1, NCAPG, BUB1, CKS2, BUB1B |
| GO:0007067 | Mitotic nuclear division | 2.01E-05 | 13 | CDK1, CDC6, CCNB2, NUF2, BUB1, TPX2, CENPF, BUB1B, NDC80, ANLN, CDC20, PBK, ASPM |
| GO:0071276 | Cellular response to cadmium ion | 4.32E-05 | 6 | MT1E, CYP1A2, MT1H, MT1X, MT1G, MT1F |
| GO:0071294 | Cellular response to zinc ion | 8.05E-05 | 6 | MT1M, MT1E, MT1H, MT1X, MT1G, MT1F |
| GO:0007094 | Mitotic spindle assembly checkpoint | 6.21E-03 | 5 | MAD2L1, BUB1, CENPF, TTK, BUB1B |
| GO:0000922 | Spindle pole | 2.80E-02 | 7 | CCNB1, CDC6, MAD2L1, PRC1, TPX2, CENPF, CDC20 |
| GO:0007062 | Sister chromatid cohesion | 3.61E-02 | 7 | MAD2L1, NUF2, BUB1, CENPF, BUB1B, NDC80, CDC20 |
| KEGG:hsa04110 | Cell cycle | 4.15E-03 | 9 | CCNB1, CDK1, CDC6, MAD2L1, CCNB2, BUB1, TTK, BUB1B, CDC20 |
| KEGG:hsa04978 | Mineral absorption | 2.54E-02 | 5 | MT1M, MT1E, MT1H, MT1X, MT1G, MT1F |
DEGs: differentially expressed genes; GO: gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes. The bold genes are hub genes.