Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 22;2019:4748312. doi: 10.1155/2019/4748312

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Xiaolong Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Effects of GHSR agonists on contractility of human prostate tissues. (a) Effects of L-692,585 (300 nM) on contractions of human prostate strips induced by electric field stimulation (tissues from n = 6 patients). (b) Effects of L-692,585 (300 nM) on contractions of human prostate strips induced by noradrenaline (tissues from n = 7 patients). (c) Effects of MK0677 (100 nM) on contractions of human prostate strips induced by the α₁-adrenoceptor agonist phenylephrine (tissues from n = 6 patients). In all series, tissue from each patient being allocated to control and GHSR agonist group in each experiment. Data are mean ± SD in frequency- and concentration-response curves (p value from 2-way ANOVA for comparison between groups as indicated in frequency and concentration response curves) (A), E_max values for each single experiment (calculated by curve fitting) in (b) and (c) (B), and from 5 of 6 experiments in (a, B) (as feasible calculation was not possible for one experiment) (^#p < 0.03 vs. control after Wilcoxon Rank Sum test), single values for 32 hertz-induced contractions in (a, C), and pEC₅₀ values for each single experiment (calculated by curve fitting) in (b) and (c) (C).