Table 3. Meta-analysis results of the top 12 SNPs from Table 2 in the VACS data.
Chr | Gene Region | SNP | Position | GEE (ind) | GEE (AR1) | GMMAT | L-BRAT (ind) | L-BRAT (AR1) | RGMMAT |
---|---|---|---|---|---|---|---|---|---|
3 | NIPA2P2 | rs551879660 | 75,146,492 | 1.81 × 10−4 | 5.86 × 10−4 | 8.98 × 10−4 | 5.26 × 10−8 | 6.41 × 10−6 | 6.49 × 10−5 |
5 | EFNA5 | rs188222191 | 105,411,547 | 7.57 × 10−6 | 1.28 × 10−5 | 1.80 × 10−4 | 2.55 × 10−7 | 5.52 × 10−7 | 1.10 × 10−5 |
rs1014278 | 105,471,506 | 1.26 × 10−5 | 8.44 × 10−6 | 3.15 × 10−4 | 1.03 × 10−6 | 5.59 × 10−7 | 2.44 × 10−5 | ||
rs75132056 | 105,480,442 | 1.31 × 10−5 | 2.00 × 10−5 | 4.24 × 10−4 | 7.31 × 10−7 | 1.27 × 10−6 | 3.56 × 10−5 | ||
8 | PSD3 | rs114629793 | 18,403,754 | 2.92 × 10−4 | 4.31 × 10−4 | 1.66 × 10−4 | 1.79 × 10−7 | 7.98 × 10−7 | 6.83 × 10−6 |
9 | OR1L4 | rs76386683 | 125,467,023 | 1.44 × 10−4 | 8.78 × 10−5 | 3.75 × 10−4 | 2.32 × 10−6 | 5.12 × 10−7 | 1.46 × 10−5 |
rs114386843 | 125,469,425 | 1.42 × 10−4 | 8.62 × 10−5 | 3.68 × 10−4 | 2.25 × 10−6 | 4.97 × 10−7 | 1.41 × 10−5 | ||
rs186274502 | 125,471,416 | 1.42 × 10−4 | 8.62 × 10−5 | 3.68 × 10−4 | 2.25 × 10−6 | 4.97 × 10−7 | 1.41 × 10−5 | ||
rs376616438 | 125,472,267 | 1.39 × 10−4 | 8.51 × 10−5 | 3.60 × 10−4 | 2.18 × 10−6 | 4.86 × 10−7 | 1.37 × 10−5 | ||
rs187855416 | 125,474,459 | 1.39 × 10−4 | 8.51 × 10−5 | 3.60 × 10−4 | 2.18 × 10−6 | 4.86 × 10−7 | 1.37 × 10−5 | ||
11 | AP000851.1 | rs139780693 | 102,509,700 | 1.15 × 10−5 | 4.16 × 10−6 | 1.07 × 10−4 | 4.04 × 10−7 | 6.05 × 10−8 | 4.41 × 10−6 |
13 | AL161616.2 | rs150191017 | 31,962,649 | 3.55 × 10−5 | 6.77 × 10−5 | 1.26 × 10−4 | 6.68 × 10−8 | 5.80 × 10−7 | 3.12 × 10−6 |
The smallest P-value among all tests at the given SNPs are in bold.