Table 1. The founding members of the Alliance of Genome Resources and the data for which the resource is the authoritative source: the NHGRI at the NIH is the primary funder for all of the resources except for Rat Genome Database, where the primary funding comes from the National Heart Lung Blood Institute.
Genome resource | Year founded | Authoritative data/annotations |
---|---|---|
Mouse Genome Database (MGD): http://www.informatics.jax.org/; Bult et al. (2019) | 1989 | Mouse gene, allele, and strain nomenclature; gene function (GO) annotations; phenotype annotations; mouse models of human disease; unified genome feature catalog for the mouse reference genome |
FlyBase: https://flybase.org/; Thurmond et al. (2019) | 1992 | Drosophila gene and allele nomenclature; gene function annotations (GO); protein annotation; phenotype annotations; fly models of human disease |
Saccharomyces Genome Database (SGD): https://yeastgenome.org/; Cherry et al. (2012) | 1993 | S. cerevisiae reference genome sequence; reference proteome and chromosomal feature annotations; standardized nomenclature for gene names; gene product annotations; gene function (GO) annotations; phenotype and human disease associations; regulatory networks; gene expression patterns; Metabolic pathways; curation of all S. cerevisiae published literature. |
Zebrafish Information Network (ZFIN): https://zfin.org/; Westerfield et al. (1997) | 1994 | Zebrafish gene, allele, and strain nomenclature; gene function (GO) annotations; gene expression annotations; phenotype annotations; zebrafish models of human disease; unified genome feature catalog for the zebrafish reference genome; reagents; catalog of Zebrafish researchers |
Gene Ontology Consortium (GOC): http://geneontology.org/: The Gene Ontology (2019) | 1998 | GO (classification of gene functions) terms and relationships among terms for Biological Process, Molecular Function, and Cellular Component; GO annotations from multiple sources |
Rat Genome Database (RGD): https://rgd.mcw.edu/; Laulederkind et al. (2018) | 1999 | Rat gene, allele, QTL, cell line, and strain nomenclature; gene function (GO) annotations; human disease, phenotype, and pathway annotations; quantitative phenotype measurement records, including expected ranges for individual rat strains. |
WormBase: https://www.wormbase.org/; Lee et al. (2018) | 2000 | C. elegans reference genome sequence and curated gene structures; nomenclature for numerous data types, including genes and alleles; gene function (GO) annotation; expression and interaction annotation; ontologies for nematode phenotypes and development; catalog of C. elegans researchers. |
GO, Gene Ontology.