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Scheme representing the autoimmune mechanisms involved in the development of renal and vascular changes. AngII, angiotensin II; ET-1, endothelin-1; IFN-γ, interferon-γ; IL-17a, interleukin 17a; NF-kB, nuclear factor-kB; ROS, reactive oxygen species; Treg, T regulatory (modified from [10]).
