Table 2.
Circulating concentrations of metabolic cytokines in the fasting state.
| Control Women | Women with PCOS | Control Men | Group | Obesity | Interaction | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Non-obese (n = 9) |
Obese (n = 8) |
Non-obese (n = 9) |
Obese (n = 8) |
Non-obese (n = 9) |
Obese (n = 9) |
P | P | P | ||
| Omentin-1 (ng/mL) | 215 ± 48 | 201 ± 75 | 211 ± 45 | 196 ± 86 | 259 ± 47 | 201 ± 89 | 0.573 | 0.044 | 0.561 | |
| Vaspin (pg/mL) | 324 ± 159 | 249 ± 185 | 349 ± 482 | 278 ± 180 | 169 ± 123 | 133 ± 61 | 0.022 A,B | 0.472 | 0.672 | |
| Lipocalin-2 (ng/mL) | 108 ± 23 | 187 ± 72 | 180 ± 95 | 150 ± 65 | 122 ± 54 | 121 ± 29 | 0.152 | 0.203 | 0.049 | |
| Adipsin (µg/mL) | 2.87 ± 0.51 | 3.46 ± 0.50 | 3.42 ± 0.89 | 3.58 ± 0.56 | 3.20 ± 0.46 | 3.47 ± 0.84 | 0.359 | 0.054 | 0.533 | |
| PAI-1 (ng/mL) | 28.2 ± 15.9 | 60.0 ± 13.8 | 33.2 ± 15.0 | 48.8 ± 22.8 | 21.2 ± 14.6 | 44.4 ± 26.6 | 0.093 | < 0.001 | 0.424 | |
| Chemerin (ng/mL) | 8.14 ± 1.54 | 10.48 ± 2.02 | 8.49 ± 1.91 | 9.32 ± 1.30 | 8.13 ± 1.73 | 8.53 ± 1.60 | 0.240 | 0.015 | 0.224 | |
| FGF-21 (pg/mL) | 392 ± 169 | 338 ± 144 | 285 ± 78 | 349 ± 84 | 258 ± 128 | 308 ± 179 | 0.102 | 0.489 | 0.346 | |
| FGF-23 (pg/mL) | 312 ± 172 | 187 ± 41 | 237 ± 134 | 195 ± 45 | 222 ± 111 | 171 ± 19 | 0.282 | 0.013 | 0.394 | |
Data are means ± SD. The mean of the three measurements, obtained at fasting before the administration of glucose, lipids and proteins on alternate days, were used for these analyses. The effects of group and obesity on continuous variables were analyzed by a two-way general linear model after applying logarithmic transformation when needed. A: p < 0.05 for the differences between control women and men. B: p < 0.05 for the differences between women with PCOS and men.