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. 2019 Oct 27;11(11):2586. doi: 10.3390/nu11112586

Figure 4.

Figure 4

Effect of PA treatment on inflammatory molecules, oxidative stress, and mitochondrial dysfunction in diet-induced NAFLD mice by real-time PCR. Graphs represent mRNA expression of transcription factors: (A) Inflammatory molecules: sirtuin 1 (SIRT-1), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), monocyte chemoattractant protein-1 (MCP-1); (B) oxidative stress: nuclear factor erythroid-derived 2-related factor 2 (Nrf2), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR); (C) mitochondrial dysfunction: peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1𝛼), uncoupling protein 3 (UCP3), carnitine palmitoyltransferase I (CPT-1). Data are mea n ±SEM. # p < 0.05, ## p < 0.01 compared with Con group; * p < 0.05, ** p < 0.01 compared with NAFLD group.