Table 2.
Body, liver, and adipose-tissue weight.
| CON | HFD | HFD + PA | HFD + Orlistat | |
|---|---|---|---|---|
| Initial body weight (g) | 16.85 ± 0.58 a | 17.29 ± 0.44 a | 17.32 ± 0.72 a | 16.68 ± 0.93 a |
| Final body weight (g) | 26.14 ± 2.67 c | 44.86 ± 2.8 a | 31.27 ± 1.53 b | 31.20 ± 1.77 b |
| Body-weight gain (g) | 9.29 ± 2.43 d | 27.57 ± 2.55 a | 13.95 ± 3.6 c | 14.52 ± 3.21 b,c |
| Total energy intake (kcal) | 749.73 ± 26.02 c | 1194.97 ± 35.89 a | 973.68 ± 29.43 b | 975.14 ± 32.32 b |
| Lean mass (g) | 0.25 ± 0.07 d | 2.07 ± 0.64 a | 0.88 ± 0.39 b | 0.57 ± 0.24 c |
| Epididymal-adipose-tissue weight (g) | 0.20 ± 0.02 d | 3.50 ± 0.4 a | 1.02 ± 0.2 b | 0.75 ± 0.09 c |
| Subcutaneous-adipose-tissue weight (g) | 0.07 ± 0.05 d | 1.50 ± 0.08 a | 0.47 ± 0.04 b | 0.23 ± 0.14 c |
| Visceral-adipose-tissue weight (g) | 0.16 ± 0.03 c | 0.33 ± 0.08 a | 0.23 ± 0.02 b | 0.21 ± 0.04 b |
| interscapular adipose tissue weight (g) | 16.85 ± 0.58 a | 17.29 ± 0.44 a | 17.32 ± 0.72 a | 16.68 ± 0.93 a |
| ALT (U/L) | 34.50 ± 3.42 b | 66.00 ± 3.54 a | 39.00 ± 1.73 b | 35.00 ± 2.65 b |
| AST (U/L) | 73.50 ± 5.45 c | 344.50 ± 0.71 a | 125.75 ± 1.49 b | 129.33 ± 4.24 b |
| TP (g/dL) | 4.68 ± 0.59 c | 5.45 ± 0.64 a | 5.05 ± 0.38 b | 5.20 ± 0.50 a,b |
| TC (mg/dL) | 107.20 ± 4.21 d | 184.50 ± 3.27 a | 116.25 ± 5.29 c | 128.00 ± 4.97 b |
| LDL-C (mg/dL) | 21.40 ± 2.70 c | 114.00 ± 4.05 a | 45.50 ± 1.78 b | 46.00 ± 5.66 b |
| HDL-C (mg/dL) | 67.67 ± 4.02 a | 33.40 ± 2.70 c | 56.50 ± 3.54 b | 54.25 ± 2.35 b |
| TG (mg/dL) | 115.20 ± 3.0 c | 261.83 ± 3.32 a | 137.50 ± 2.36 b | 113.25 ± 1.66 c |
All data represent mean values ± SEM. a-h Values with different superscripts were significantly different with p < 0.05 as analyzed by Dunnertt’s multiple-range tests. ALT, alanine aminotransferase; AST, aspartate aminotransferase; TP, total protein; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol, TG, triglyceride.