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. 2019 Nov 1;11(11):2613. doi: 10.3390/nu11112613

Table 4.

Plasma concentrations of leucine, methionine, arginine, and glycine.

P4 Protein Casein Protein Whey Protein Soy Protein Pea Protein
Leucine
Baseline, μmol/L 116.13 ± 23.59 116.12 ± 19.87 115.76 ± 19.96 118/83 ± 20.37 113.92 ± 21.43
iCmax, μmol/L 237.70 ± 51.22 266.38 ± 41.30 282.64 ± 80.86 a 152.46 ± 32.79 abc 165.52 ± 27.22 abc
iAUC,μmol/L*min 25448 ± 5647 26623 ± 5210 c 32799 ± 8505 a 16754 ± 4122 abc 18731 ± 3763 abc
Methionine
Baseline, μmol/L 24.7 ± 4.23 24.59 ± 2.60 24.98 ± 2.91 24.61 ± 2.26 23.74 ± 3.53
iCmax, μmol/L 24.62 ± 6.21 49.97 ± 8.24 ac 27.33 ± 7.37 12.64 ± 2.99 abc 2.88 ± 1.55 abc
iAUC, μmol/L*min 1936 ± 635 4360 ± 970 ac 2356 ± 794 931 ± 323 abc 137 ± 105 abc
Arginine
Baseline, μmol/L 100.11 ± 17.20 101.54 ± 15.62 101.30 ± 14.68 96.13 ± 19.00 98.09 ± 12.46
iCmax, μmol/L 90.96 ± 16.55 83.46 ± 13.88 ac 60.43 ± 9.58 a 102.39 ± 20.58 bc 112.45 ± 24.93 abc
iAUC, μmol/L*min 7979 ±1551 6534 ± 1631 a 5606 ± 1029 a 10740 ± 3257 abc 10719 ± 2426 abc
Glycine
Baseline, μmol/L 281.25 ± 80.84 289.62 ± 99.50 280.54 ± 81.82 290.37 ± 82.31 273.24 ± 86.45
iCmax, μmol/L 37.84 ± 21.02 34.50 ± 23.14 29.76 ±16.54 64.71 ± 43.01 bc 50.97 ± 26.2 bc
iAUC, μmol/L*min 1712 ± 1469 1447 ± 1147 1106 ± 735 3461 ± 2056 abc 3189 ± 2413 bc

All data are presented as mean ± SD. iCmax, maximum concentration above baseline; iAUC, incremental area under the curve. a indicates significant difference compared to P4 protein; b indicates significant difference compared to casein protein; c indicates significant difference compared to whey protein.