Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hck-binding compounds inhibit Hck-U32L target protein interaction with the VSL12 probe peptide in a concentration-dependent manner. Four confirmed hit compounds from the FP screen of the ChemBridge 50,000 compound library were purchased as powders, and re-tested in the screening assay over a wide range of concentrations as shown (n = 2; each data point in triplicate). The IC50 values from each of the two determinations ± S.E. are shown at the top left in each graph.
