Table 2.
Crude hazard ratios based on Cox proportional hazards model to assess characteristics associated with all-cause mortality in patients with neuroendocrine tumors (N=96).
| Characteristica and category | Total deaths (N) | Crude hazard ratiob (95% CI) | P value | |
| Age at diagnosis (years) | ||||
|
|
≤65 | 13 | Reference |
|
| >65 | 23 | 3.05 (1.54-6.06) | .001 | |
| Sex | ||||
|
|
Male | 16 | 4.33 (1.51-12.37)c | .01 |
| Female | 20 | Reference |
|
|
| Neuroendocrine tumor site | ||||
|
|
Lung | 15 | 0.89 (0.37-2.13) | .80 |
| Gastroenteropancreatic | 13 | 0.25 (0.10-0.61) | .002 | |
| Other | 8 | Reference |
|
|
| Grade at diagnosis | ||||
|
|
1 | 11 | Reference |
|
| 2-3 | 7 | 1.81 (0.69-4.72) | .23 | |
| Remoteness category | ||||
|
|
City | 21 | 1.56 (0.80-3.03) | .19 |
| Regional/remote | 15 | Reference |
|
|
| Resection surgery | ||||
|
|
No | 20 | 3.25 (1.68-6.30) | .001 |
| Yes | 16 | Reference |
|
|
| Stage at diagnosis | ||||
|
|
Localized/regional | 18 | Reference |
|
| Distant | 17 | 2.15 (1.10-4.18) | .03 | |
| Tumor size category | ||||
|
|
<20 mm | 9 | Reference |
|
| ≥20 mm | 13 | 1.43 (0.61-3.36) | .41 | |
aInformation on grade was missing at diagnosis for 34 patients, on resection surgery for 1 patient, on stage at diagnosis for 1 patient, and on tumor size for 27 patients.
bHazard ratios were based on Cox proportional hazards model.
cHazard ratio adjusted for time interaction.