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. 2019 Nov 20;5(2):e12849. doi: 10.2196/12849

Table 2.

Crude hazard ratios based on Cox proportional hazards model to assess characteristics associated with all-cause mortality in patients with neuroendocrine tumors (N=96).

Characteristica and category Total deaths (N) Crude hazard ratiob (95% CI) P value
Age at diagnosis (years)

≤65 13 Reference
>65 23 3.05 (1.54-6.06) .001
Sex

Male 16 4.33 (1.51-12.37)c .01
Female 20 Reference
Neuroendocrine tumor site

Lung 15 0.89 (0.37-2.13) .80
Gastroenteropancreatic 13 0.25 (0.10-0.61) .002
Other 8 Reference
Grade at diagnosis

1 11 Reference
2-3 7 1.81 (0.69-4.72) .23
Remoteness category

City 21 1.56 (0.80-3.03) .19
Regional/remote 15 Reference
Resection surgery

No 20 3.25 (1.68-6.30) .001
Yes 16 Reference
Stage at diagnosis

Localized/regional 18 Reference
Distant 17 2.15 (1.10-4.18) .03
Tumor size category

<20 mm 9 Reference
≥20 mm 13 1.43 (0.61-3.36) .41

aInformation on grade was missing at diagnosis for 34 patients, on resection surgery for 1 patient, on stage at diagnosis for 1 patient, and on tumor size for 27 patients.

bHazard ratios were based on Cox proportional hazards model.

cHazard ratio adjusted for time interaction.