. 2019 Oct 23;11(11):2562. doi: 10.3390/nu11112562

Table 4.

Comparison of urinary parameters in the placebo and amino acid supplementation groups.

	Placebo	Tryptophan	Glycine	Glycine + Tryptophan
Urinary uric acid excretion (mg/kg/h)	0.441 (0.079) ^a	0.453 (0.092) ^a	0.596 (0.129) ^b	0.653 (0.153) ^b
Urinary creatinine excretion (mg/kg/h)	1.15 (0.19) ^a	1.26 (0.22) ^a,b	1.43 (0.33) ^b	1.16 (0.26) ^a
Urinary uric acid/creatinine (mg/mg)	0.40 (0.11) ^a	0.37 (0.10) ^a	0.44 (0.13) ^a	0.58 (0.16) ^b
Urate clearance (mL/min)	7.5 (1.5) ^a	7.7 (1.9) ^a	9.9 (2.6) ^b	11.0 (2.5) ^b
Creatinine clearance (mL/min)	150 (15) ^a	176 (41) ^a,b	187 (39) ^b	156 (29) ^a
Urinary pH	6.22 (0.44) ^a	6.23 (0.55) ^a	6.54 (0.64) ^a,b	6.83 (0.35) ^b

Data are presented as the mean ± standard deviation. Means of urinary parameters with different superscript letters are significantly different among the four groups at p < 0.05 by the Tukey–Kramer test. Urinary uric acid and creatinine excretion and urate and creatinine clearance were analyzed in urine specimens that were collected for 2 h after complete urine excretion following ingestion of the supplement.