Table 5.
Liver status, oxidative stress markers. Pre-intervention and Week 28.
| Pre-intervention | HF | HF+ | LF | LF+ | |
|---|---|---|---|---|---|
| AA (nmol/g) | 1283.5 ± 379.51 | 1404.5 ± 497.99 | 1357 ± 457.91 | 1287.75 ± 573.73 | 1770 ± 380.30 |
| BH2/BH4 | 0.21 ± 0.05 | 0.20 ± 0.12 | 0.30 ± 0.16 | 0.23 ± 0.10 | 0.23 ± 0.20 |
| L-arg (nmol/g) | 32.96 ± 8.73 | 22.10 ± 9.56 | 24.95 ± 6.47 | 23.60 ± 6.50 | 36.74 ± 10.80 |
| ADMA (nmol/g) | 0.73 ± 0.92 | 0.99 ± 0.80 | 0.70 ± 0.60 | 0.50 ± 0.60 | 0.91 ± 1.10 |
| GSH (nmol/g) | 3160.63 ± 503.63 | 3440.40 ± 487.40 | 3138.63 ± 301.32 | 3072.25 ± 305.80 | 3303.25 ± 170.97 |
| GSSG (nmol/g) | 317.72 ± 49.40 | 300.52 ± 69.90 | 295.40 ± 68.50 | 322.70 ± 32.30 | 324.80 ± 61.96 |
| SOD (U/mg) | 2489.5 ± 432.10 | 2783.90 ± 786.60 | 2512.00 ± 642.80 | 3206.40 ± 1059.80 | 2899.13 ± 502.82 |
| αToc (nmol/g) j | 1.71 (1.22–2.19) | 2.87 (0.90–4.84) | 9.43 (3.68–15.18) a, b, c | 3.49 (1.95–5.02) | 8.61 (4.98–12.24) a, b, c |
AA, ascorbic acid; BH2/BH4, dihydrobiopterin/tetrahydrobiopterin ratio; L-arg, L-arginine; ADMA, asymmetric dimethylarginine; GSH, glutathione; GSSG, oxidized glutathione; MDA, malondialdehyde; SOD, superoxide dismutase; α-Toc, alpha-tocopherol. Data are presented as mean ± standard deviation. j Data are presented as geometric mean with 95 confidence intervals. a p < 0.001, compared with Pre-intervention. b p < 0.01, compared with HF. c p < 0.05, compared with LF.