Skip to main content
. 2019 Oct 23;11(11):1626. doi: 10.3390/cancers11111626

Figure 1.

Figure 1

Lysophosphatidic acid (LPA) metabolism and signaling. AC: adenylyl cyclase; AKT: AKR mouse thymoma (albeit the name does not represent its function); ATX: Autotaxin; cAMP: cyclic adenosine monophosphate; DAG: diacylglycerol; EGFR: Epidermal growth factor receptor; ER: endoplasmic reticulum; ERK: extracellular signal-regulated kinase; GPAT: glycerol-3-phosphate acyltransferase; IP3: Inositol trisphosphate; LPAR: lysophosphatidic acid receptor; LPC: l;ysophosphatidylcholine; LPPs: lipid phosphate phosphatases; MAG: monoacylglycerol; MAPK: Mitogen activated protein kinase; PA: phosphatidic acid; PI3K: Phosphoinositide 3-kinase; PLA: phospholipase A; PLC: Phospholipase C; PPARγ: Peroxisome Proliferator-Activated Receptor gamma; Rho: Ras homolog gene; ROCK: Rho-associated, coiled-coil-containing protein kinase; SRF: serum response factor.