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. 2019 Oct 23;11(11):1626. doi: 10.3390/cancers11111626

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Hepatocyte specific ATX production driven by fat, glucose, phospholipids and Hepatitis C virus (HCV) infection can promote hepatic stellate cells (HSCs) activation, steatosis and hepatocellular carcinoma (HCC) growth.